Tacrolimus is an immunosuppressant drug used primarily to prevent organ transplant rejection and treat autoimmune diseases. It works by inhibiting T-cell activation, reducing the body’s immune response.
This test measures the Tacrolimus level in blood to ensure:
✅ Effective immunosuppression (preventing organ rejection)
✅ Avoiding toxicity (high levels can cause kidney and neurological damage)
✅ Adjusting dosage based on individual metabolism
✔ Sample Type: Blood (usually from a vein)
✔ Best Time to Test: Before the next dose (trough level) for accurate monitoring
✔ Results Time: Usually within 24 hours
| Condition | Therapeutic Range (ng/mL) |
|---|---|
| Kidney Transplant | 5 – 15 ng/mL |
| Liver Transplant | 5 – 20 ng/mL |
| Heart Transplant | 8 – 20 ng/mL |
| Autoimmune Diseases | 5 – 10 ng/mL |
⚠️ Levels above 20 ng/mL may indicate toxicity!
🚨 Risk: Organ rejection due to insufficient immunosuppression
🔹 Possible Causes:
🚨 Risk: Toxicity (kidney damage, neurotoxicity, high blood pressure)
🔹 Possible Causes:
🔸 Nephrotoxicity (kidney damage)
🔸 Neurotoxicity (tremors, headaches, confusion, seizures)
🔸 High blood pressure
🔸 Increased blood sugar (risk of diabetes)
🔸 Electrolyte imbalances (low magnesium, high potassium)
✅ Diet: Avoid grapefruit juice, as it increases Tacrolimus levels
✅ Other Medications: Some drugs increase or decrease Tacrolimus metabolism
✅ Liver & Kidney Function: Tacrolimus is metabolized in the liver (CYP3A4 enzyme) and excreted by the kidneys
Original price was: ₹2,000.00.₹1,499.00Current price is: ₹1,499.00.