The Hepatitis C Virus (HCV) Genotyping Test identifies the specific genetic strain (genotype) of HCV present in an infected individual. This test is crucial for determining the most effective treatment plan since different genotypes respond differently to antiviral medications.
✅ Guides Treatment Selection – Different HCV genotypes require different antiviral regimens.
✅ Predicts Treatment Duration & Success – Some genotypes require longer treatment or combination therapies.
✅ Assesses Risk of Chronic Infection – Some genotypes have a higher likelihood of leading to chronic hepatitis, cirrhosis, or liver cancer.
✅ Used Before Initiating Therapy – Helps healthcare providers choose the most effective direct-acting antiviral (DAA) treatment.
🩸 Blood Sample Collection – A blood sample is drawn and analyzed using reverse transcription polymerase chain reaction (RT-PCR) to detect the genetic makeup of the virus.
Hepatitis C has six main genotypes (1–6), with further subtypes (e.g., 1a, 1b).
| Genotype | Global Prevalence | Treatment Considerations |
|---|---|---|
| Genotype 1 (1a, 1b) | Most common worldwide (~46%) | Requires longer treatment but responds well to DAAs. |
| Genotype 2 | Common in Europe, Japan, China | Higher cure rates with shorter treatment. |
| Genotype 3 | Common in South Asia, Australia | Higher risk of fatty liver & liver disease progression. Harder to treat. |
| Genotype 4 | Common in the Middle East, Africa | Responds well to DAAs but may require longer treatment. |
| Genotype 5 | Common in South Africa | Rare, but still treatable with DAAs. |
| Genotype 6 | Found in Southeast Asia | Similar treatment response as genotype 4. |
📌 Genotype 1 is the most common worldwide and has historically been the most difficult to treat, but modern direct-acting antivirals (DAAs) have significantly improved cure rates.
🔬 If HCV RNA is detected:
🔬 If HCV RNA is NOT detected:
🩺 HCV Antibody (IgG) Test – Screens for past or present HCV exposure.
🧪 HCV RNA PCR Test – Confirms active infection and measures viral load.
🩸 Liver Function Tests (LFTs) – Checks for liver damage (ALT, AST, bilirubin).
📊 FibroScan or Liver Biopsy – Assesses fibrosis, cirrhosis, or liver damage severity.
✔ HCV Genotyping is essential for choosing the most effective treatment.
✔ Different genotypes require different antiviral medications and treatment durations.
✔ Genotype 1 is the most common, while Genotype 3 has a higher risk of severe liver disease.
✔ Modern DAAs have high cure rates for all genotypes, with shorter treatment durations and fewer side effects.
Original price was: ₹4,500.00.₹3,899.00Current price is: ₹3,899.00.