The Chromogranin A (CgA) test measures the level of CgA protein in the blood, which is a biomarker for neuroendocrine tumors (NETs). It helps in diagnosing, monitoring, and assessing treatment response for NETs, including carcinoid tumors, pheochromocytomas, pancreatic NETs, and neuroblastomas.
🔹 To diagnose neuroendocrine tumors (NETs) – Carcinoid tumors, pheochromocytomas, pancreatic NETs
🔹 To monitor tumor progression or treatment response – Especially for patients already diagnosed with NETs
🔹 To differentiate NETs from other conditions – Helps distinguish from other causes of symptoms like flushing, diarrhea, or high blood pressure
Typical range: <100 ng/mL (varies by laboratory)
Elevated levels may indicate a neuroendocrine tumor or other conditions
| CgA Level | Possible Causes |
|---|---|
| Mildly Elevated | – Chronic gastritis (H. pylori infection) – Proton pump inhibitors (PPIs) (e.g., Omeprazole, Pantoprazole) – Chronic kidney or liver disease |
| Moderately to Highly Elevated | – Neuroendocrine Tumors (NETs) (Carcinoid tumors, Pheochromocytomas, Pancreatic NETs) – Neuroblastoma – Medullary Thyroid Carcinoma (MTC) – Adrenal Gland Tumors (Pheochromocytoma) |
🚫 Proton Pump Inhibitors (PPIs) – Can falsely elevate CgA (stop 1-2 weeks before testing)
💊 Chronic Kidney Disease (CKD) – Can cause mild to moderate elevation
🍽 Recent Meals – Fasting before the test is recommended for accurate results
🔹 24-hour Urine 5-HIAA (5-Hydroxyindoleacetic Acid) – Detects serotonin breakdown (for carcinoid tumors)
🔹 Metanephrines & Catecholamines (Plasma or Urine) – To diagnose pheochromocytoma
🔹 Imaging Tests (CT, MRI, PET Scan with Ga-68 DOTATATE) – To locate NETs
✅ Repeat the test after stopping PPIs (if applicable)
✅ Further NET-specific testing (e.g., 5-HIAA, imaging)
✅ Consult an endocrinologist or oncologist for further evaluation
Original price was: ₹3,200.00.₹1,999.00Current price is: ₹1,999.00.