The F Bile Acid Test measures the levels of bile acids in the blood. It is primarily used to assess liver function, bile flow, and certain digestive disorders.
🔹 Bile acids are produced in the liver from cholesterol and stored in the gallbladder.
🔹 They help digest fats and absorb fat-soluble vitamins (A, D, E, K).
🔹 After digestion, bile acids are reabsorbed into the bloodstream and recycled by the liver (enterohepatic circulation).
✅ Detects liver diseases (Hepatitis, Cirrhosis, Fatty Liver)
✅ Diagnoses Intrahepatic Cholestasis of Pregnancy (ICP) (Liver disorder in pregnancy causing severe itching)
✅ Evaluates bile flow problems (Gallstones, Tumors, Primary Biliary Cholangitis)
✅ Assesses digestive disorders (Bile acid diarrhea, malabsorption)
| Test Type | Normal Range |
|---|---|
| Fasting Serum Bile Acids | 0 – 10 µmol/L |
| Postprandial Serum Bile Acids | 0 – 19 µmol/L |
| Urine Bile Acids | Normally Absent |
🔹 High bile acid levels suggest liver disease, cholestasis, or bile acid malabsorption.
| Condition | Cause |
|---|---|
| Intrahepatic Cholestasis of Pregnancy (ICP) | Impaired bile acid clearance leads to buildup in blood |
| Liver Disease (Hepatitis, Cirrhosis, Fatty Liver) | Liver cannot process bile acids properly |
| Bile Duct Obstruction (Gallstones, Tumors, Strictures) | Bile cannot flow properly |
| Primary Biliary Cholangitis (PBC) & Primary Sclerosing Cholangitis (PSC) | Autoimmune diseases affecting bile ducts |
| Bile Acid Malabsorption (Crohn’s Disease, IBS-D, SIBO) | Bile acids not absorbed properly, leading to diarrhea |
☑ Severe itching (pruritus), especially at night
☑ Jaundice (yellow skin & eyes, if severe)
☑ Dark urine (bilirubin buildup)
☑ Pale or clay-colored stools (low bile flow into intestines)
☑ Diarrhea & fat malabsorption (in bile acid malabsorption)
Sample: Blood (serum) or urine
Fasting: Recommended for 12 hours for accuracy
Method: Enzymatic or chromatographic assays
🔹 For Intrahepatic Cholestasis of Pregnancy (ICP):
Ursodeoxycholic Acid (UDCA) to lower bile acids & reduce itching
Early delivery may be needed if fetal distress is suspected
🔹 For Liver & Bile Duct Diseases:
Treat underlying liver disease (hepatitis, cirrhosis, PBC, PSC)
Gallbladder removal (cholecystectomy) if gallstones block bile flow
Bile acid sequestrants (Cholestyramine, Colesevelam) to bind excess bile acids
🔹 For Bile Acid Malabsorption:
Low-fat diet to reduce bile acid production
Bile acid binders to control diarrhea
✅ Bile acids help with fat digestion & liver function.
✅ High levels indicate liver disease, pregnancy-related cholestasis, or bile acid malabsorption.
✅ Severe itching & diarrhea are common symptoms.
✅ Treatment depends on the cause—medications, surgery, or dietary changes.
₹1,450.00 Original price was: ₹1,450.00.₹1,099.00Current price is: ₹1,099.00.