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Varicella Zoster Virus (VZV) IgG

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Varicella Zoster Virus (VZV) IgG Test

The VZV IgG test detects IgG antibodies in the blood, which indicate past infection or immunity to Varicella Zoster Virus (VZV)—the virus that causes chickenpox (varicella) and shingles (herpes zoster).

Why is the VZV IgG Test Done?

Doctors may recommend this test to:
✅ Check if you are immune to VZV (from past infection or vaccination)
✅ Confirm past chickenpox or shingles infection
✅ Assess immunity in pregnant women (to prevent congenital varicella syndrome)
✅ Evaluate healthcare workers or people in high-risk jobs
✅ Determine vaccination needs

Interpreting VZV IgG Test Results

🟢 Positive VZV IgG

  • You are immune due to a past infection or vaccination
  • You are unlikely to get chickenpox again, but shingles can still occur later in life

🔴 Negative VZV IgG

  • No immunity detected
  • You may be at risk of chickenpox and should consider vaccination if recommended

Difference Between VZV IgM & IgG Tests

Test Indicates When It Appears What It Means
IgM Recent or active infection Few days after infection Temporary, disappears after weeks/months
IgG Past infection or immunity Weeks after infection or vaccination Stays for life, indicates immunity

What If My VZV IgG is Positive?

✅ If you never had chickenpox, a positive IgG means you are protected
✅ If you had shingles, a positive IgG confirms past exposure
✅ If you are pregnant, a positive IgG means you likely don’t need the vaccine