Phosphatidylserine IgM Antibody

Phosphatidylserine IgM Antibody Test

The Phosphatidylserine IgM Antibody Test is used to detect antibodies against phosphatidylserine, a type of phospholipid found in cell membranes. It helps diagnose antiphospholipid syndrome (APS) and related autoimmune conditions, which can cause abnormal blood clotting.


Why is the Test Done?

✅ Diagnose Antiphospholipid Syndrome (APS) – A disorder causing excessive blood clotting
✅ Evaluate unexplained blood clots (deep vein thrombosis, pulmonary embolism, stroke)
✅ Investigate recurrent miscarriages or pregnancy complications
✅ Assess autoimmune diseases like lupus (SLE)


Normal Range & Interpretation

Test Result Interpretation
Negative (<12 U/mL) No significant antibodies detected
Borderline (12-20 U/mL) May indicate early or mild antibody presence
Positive (>20 U/mL) Suggests possible APS or autoimmune disorder

📌 High IgM levels indicate an active immune response but may not always cause disease. A repeat test is needed after 12 weeks for confirmation.


Conditions Associated with High Phosphatidylserine IgM

🔹 Antiphospholipid Syndrome (APS) – Causes blood clots and pregnancy loss
🔹 Systemic Lupus Erythematosus (SLE) – Autoimmune disorder affecting multiple organs
🔹 Chronic Infections – Some infections can trigger temporary antibody production
🔹 Multiple Sclerosis (MS) & Other Autoimmune Diseases – Less common association


Symptoms Suggesting APS or Autoimmune Disease

⚠ Blood clotting symptoms:
✔ Deep vein thrombosis (DVT) – Leg swelling, pain
✔ Pulmonary embolism – Shortness of breath, chest pain
✔ Stroke or mini-stroke (TIA) – Sudden weakness, speech problems
✔ Recurrent miscarriages – Especially after 10 weeks of pregnancy


Next Steps After a Positive Test

🔬 Confirmatory Tests:
✔ Repeat Phosphatidylserine IgM after 12 weeks
✔ Other APS markers:

  • Phosphatidylserine IgG & IgA
  • Lupus Anticoagulant (LA)
  • Anti-Cardiolipin Antibodies
  • Beta-2 Glycoprotein I Antibodies

💊 Treatment for APS (if diagnosed):
✔ Blood thinners (anticoagulants) – Warfarin, heparin
✔ Aspirin (low-dose) – Reduces clot risk
✔ Immunosuppressants (if linked to lupus)

Original price was: ₹2,500.00.Current price is: ₹2,299.00.

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