The BK Virus Quantitative PCR (Polymerase Chain Reaction) Test is used to measure the amount of BK virus (BKV) DNA in a patient’s blood, urine, or other body fluids. This test is particularly important for kidney transplant patients and those with weakened immune systems.
✅ Monitors BK virus reactivation in kidney transplant recipients
✅ Detects BK virus-associated nephropathy (BKVN), which can lead to kidney graft failure
✅ Assesses infection in bone marrow transplant patients and immunocompromised individuals
✅ Helps diagnose hemorrhagic cystitis in stem cell transplant patients
🔹 Specimen Type: Blood (plasma/serum) or Urine
🔹 Method: Real-Time PCR (RT-PCR)
🔹 Preparation: No fasting or special preparation needed
| BK Virus DNA Level (copies/mL) | Interpretation |
|---|---|
| Undetectable | No active BK virus infection |
| <10,000 | Low viral load, may be an early infection |
| 10,000 – 100,000 | Moderate infection, close monitoring required |
| >100,000 | High viral load, risk of BK virus nephropathy (BKVN) |
🔹 A high BK viral load in blood (>10,000 copies/mL) may indicate kidney damage.
🔹 A high viral load in urine but low in blood suggests early-stage infection.
BK Virus Nephropathy (BKVN) occurs when the virus infects the transplanted kidney, leading to inflammation and possible graft loss.
Routine monitoring is recommended for kidney transplant patients, especially in the first 6–12 months post-transplant.
If BK viremia (virus in blood) is detected, doctors may adjust immunosuppressive therapy to control the infection.
🔹 No specific antiviral drugs are approved for BK virus.
🔹 Management includes:
Reducing immunosuppression (e.g., lowering tacrolimus or mycophenolate dose).
Using antiviral agents (Cidofovir, Leflunomide) in severe cases.
Monitoring kidney function (serum creatinine, biopsy if needed).
✅ BK Virus is common but can be dangerous in immunocompromised patients.
✅ High viral load (>100,000 copies/mL) in blood is a warning sign for kidney transplant patients.
✅ Regular screening helps prevent BK virus nephropathy.
✅ Early detection allows adjustment of immunosuppressive therapy.
Original price was: ₹4,500.00.₹2,999.00Current price is: ₹2,999.00.