Fever Profile 1.1 – Test Details & Precautions

The Fever Profile 1.1 is a diagnostic panel used to detect common causes of fever, including Malaria, Typhoid, and other infections. It includes the following tests:

1. Malaria Antigen Test – Detects malaria infection.
2. Widal Test – Checks for Typhoid fever.
3. Typhidot IgG/IgM Test – Identifies Typhoid antibodies.
4. CBC (Complete Blood Count) – Evaluates overall blood health and infection signs.

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1. Malaria Antigen Test

✔ Purpose: Detects Plasmodium falciparum & Plasmodium vivax antigens in the blood.
✔ When to Test? If experiencing fever with chills, sweating, and body aches.

🔹 Results Interpretation:
✔ Positive – Malaria infection present.
✔ Negative – No malaria detected, but further testing may be needed if symptoms persist.

✅ Precautions:

• No fasting required.
• If fever continues, a repeat test may be necessary.

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2. Widal Test

✔ Purpose: Detects antibodies against Salmonella typhi & paratyphi (Typhoid Fever).
✔ When to Test? After 5-7 days of fever for accurate results.

🔹 Results Interpretation:
✔ Positive (≥1:160 titer) – Suggests Typhoid infection (further confirmation may be needed).
✔ Negative – No significant typhoid infection detected.

✅ Precautions:

• May give false-positive or false-negative results (should be confirmed with Typhidot or blood culture).
• Avoid testing too early (<5 days of fever) for better accuracy.

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3. Typhidot IgG/IgM Test

✔ Purpose: Detects IgM (recent) & IgG (past) antibodies against Salmonella typhi.
✔ When to Test? After 2-3 days of fever.

🔹 Results Interpretation:
✔ IgM Positive – Recent/active Typhoid infection.
✔ IgG Positive – Past Typhoid infection or immunity.
✔ Both Negative – No Typhoid infection.

✅ Precautions:

• More specific than Widal test.
• No fasting required.

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4. CBC (Complete Blood Count)

✔ Purpose: Identifies infection, anemia, or blood abnormalities.
✔ What It Detects?

• Increased WBCs – Suggests bacterial infection.
• Low platelets – Common in Dengue or Malaria.
• Low Hemoglobin (Hb) – May indicate anemia.

✅ Precautions:

• No fasting required.
• Can be done anytime during fever episodes.

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Summary of Fever Profile 1.1

Test	Purpose	When to Test?	What it Detects?
Malaria Antigen	Detects Malaria infection	If fever with chills/sweats	Malaria (P. vivax, P. falciparum)
Widal Test	Typhoid fever screening	After 5-7 days of fever	Salmonella typhi/paratyphi
Typhidot IgG/IgM	Confirms Typhoid infection	After 2-3 days of fever	Recent (IgM) or past (IgG) Typhoid
CBC	Detects infections/anemia	Anytime during fever	WBC, platelet count, hemoglobin

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General Precautions:

✔ No fasting required.
✔ Best tested based on fever duration for accurate results.
✔ False positives can occur in Widal & Typhidot tests—blood culture may be needed for confirmation.
✔ If symptoms persist, additional tests for Dengue, Leptospirosis, or Viral Fever may be necessary.