Dengue Profile 1.1 – Dengue IgG, IgM & NS1 ELISA Test Details & Precautions

The Dengue Profile 1.1 is a diagnostic test used to detect dengue virus infection at different stages. It includes:

1. NS1 Antigen ELISA – Detects early infection (Day 1-7).
2. Dengue IgM Antibody – Detects recent or active infection.
3. Dengue IgG Antibody – Detects past infection or immunity.

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1. NS1 Antigen ELISA

Purpose:

• Identifies early-stage dengue infection (before antibodies develop).
• Positive in the first 7 days of illness.

🔹 Results Interpretation:
✔ Positive – Active dengue infection.
✔ Negative – No infection or late-stage dengue.

✅ Precautions:

• No fasting required.
• Best performed within Day 1-7 of fever onset for accuracy.

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2. Dengue IgM Antibody

Purpose:

• Detects recent infection (after 5-7 days of symptoms).
• Remains positive for up to 3 months.

🔹 Results Interpretation:
✔ Positive – Recent or ongoing dengue infection.
✔ Negative – No recent infection or very early stage.

✅ Precautions:

• No fasting required.
• Avoid testing too early (<5 days of fever), as antibodies take time to develop.

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3. Dengue IgG Antibody

Purpose:

• Indicates past infection or immunity.
• Remains detectable for months or years.

🔹 Results Interpretation:
✔ Positive – Past infection or long-term immunity.
✔ Negative – No previous exposure to dengue virus.

✅ Precautions:

• No fasting required.
• May be used in paired testing with IgM for better accuracy.

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Summary of Dengue Profile 1.1

Test	Purpose	When to Test?	What it Detects?
NS1 ELISA	Early-stage diagnosis	Day 1-7 of fever	Active dengue infection
IgM Antibody	Detects recent infection	After Day 5-7	Recent dengue infection
IgG Antibody	Detects past infection	After 7-10 days	Past exposure or immunity

General Precautions:

✔ No fasting required.
✔ Best performed based on fever duration for accurate results.
✔ If results are unclear, a repeat test after a few days may be needed.
✔ Drink plenty of fluids and monitor for severe symptoms (bleeding, dehydration).