Phosphatidylserine IgM Antibody

Phosphatidylserine IgM Antibody Test

The Phosphatidylserine IgM Antibody Test is used to detect antibodies against phosphatidylserine, a type of phospholipid found in cell membranes. It helps diagnose antiphospholipid syndrome (APS) and related autoimmune conditions, which can cause abnormal blood clotting.


Why is the Test Done?

Diagnose Antiphospholipid Syndrome (APS) – A disorder causing excessive blood clotting
Evaluate unexplained blood clots (deep vein thrombosis, pulmonary embolism, stroke)
Investigate recurrent miscarriages or pregnancy complications
Assess autoimmune diseases like lupus (SLE)


Normal Range & Interpretation

Test Result Interpretation
Negative (<12 U/mL) No significant antibodies detected
Borderline (12-20 U/mL) May indicate early or mild antibody presence
Positive (>20 U/mL) Suggests possible APS or autoimmune disorder

📌 High IgM levels indicate an active immune response but may not always cause disease. A repeat test is needed after 12 weeks for confirmation.


Conditions Associated with High Phosphatidylserine IgM

🔹 Antiphospholipid Syndrome (APS) – Causes blood clots and pregnancy loss
🔹 Systemic Lupus Erythematosus (SLE) – Autoimmune disorder affecting multiple organs
🔹 Chronic Infections – Some infections can trigger temporary antibody production
🔹 Multiple Sclerosis (MS) & Other Autoimmune Diseases – Less common association


Symptoms Suggesting APS or Autoimmune Disease

Blood clotting symptoms:
✔ Deep vein thrombosis (DVT) – Leg swelling, pain
✔ Pulmonary embolism – Shortness of breath, chest pain
✔ Stroke or mini-stroke (TIA) – Sudden weakness, speech problems
✔ Recurrent miscarriages – Especially after 10 weeks of pregnancy


Next Steps After a Positive Test

🔬 Confirmatory Tests:
Repeat Phosphatidylserine IgM after 12 weeks
Other APS markers:

  • Phosphatidylserine IgG & IgA
  • Lupus Anticoagulant (LA)
  • Anti-Cardiolipin Antibodies
  • Beta-2 Glycoprotein I Antibodies

💊 Treatment for APS (if diagnosed):
Blood thinners (anticoagulants) – Warfarin, heparin
Aspirin (low-dose) – Reduces clot risk
Immunosuppressants (if linked to lupus)

Original price was: ₹2,500.00.Current price is: ₹2,299.00.

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