The TSH Receptor Autoantibodies (TRAb) test detects autoantibodies that target the thyroid-stimulating hormone (TSH) receptor. These antibodies play a key role in Graves’ disease, an autoimmune disorder that causes hyperthyroidism (overactive thyroid).
✅ Diagnose Graves’ Disease – Confirms an autoimmune cause of hyperthyroidism.
✅ Differentiate Graves’ Disease from Other Thyroid Disorders – Helps distinguish it from toxic multinodular goiter or thyroiditis.
✅ Predict Graves’ Ophthalmopathy (Thyroid Eye Disease, TED) – High TRAb levels indicate increased risk of eye involvement.
✅ Monitor Treatment Response – Tracks antibody levels during treatment (antithyroid drugs, radioiodine, or surgery).
✅ Assess Risk of Neonatal Hyperthyroidism – In pregnant women with Graves’ disease, TRAb can cross the placenta and affect the baby.
1️⃣ Stimulating Antibodies (TSI – Thyroid Stimulating Immunoglobulins)
| Result | Interpretation |
|---|---|
| Negative (<1.75 IU/L) | No autoimmune thyroid disease detected. |
| Borderline (1.75–2.0 IU/L) | Possible early or mild disease; requires further evaluation. |
| Positive (>2.0 IU/L) | Suggests Graves’ Disease or risk of neonatal hyperthyroidism in pregnancy. |
(Reference ranges vary by lab and test method used.)
| Condition | TRAb Level | Effect on Thyroid |
|---|---|---|
| Graves’ Disease | High (↑) | Overactive thyroid (hyperthyroidism) |
| Hashimoto’s Thyroiditis (Rare Cases) | Mildly Elevated | Can fluctuate between hyper- and hypothyroidism |
| Neonatal Thyrotoxicosis | High in Pregnant Mother | May cause transient hyperthyroidism in newborn |
| Post-Treatment Monitoring | Decrease in levels | Indicates effective treatment |
📌 TSH, Free T3, Free T4 – To evaluate thyroid function.
📌 Thyroid Ultrasound & Doppler – Helps assess thyroid size and blood flow.
📌 Radioactive Iodine Uptake (RAIU) Scan – Differentiates Graves’ Disease from thyroiditis.
📌 Eye Exam – If Graves’ ophthalmopathy is suspected.
✔ TRAb is a key marker for diagnosing Graves’ disease.
✔ High TRAb in pregnancy may indicate risk of neonatal hyperthyroidism.
✔ Monitoring TRAb helps assess treatment response and relapse risk.
Original price was: ₹2,499.00.₹1,499.00Current price is: ₹1,499.00.