Book A Test

Aspergillus IgE, IgG, IgM Panel

Original price was: ₹3,999.00.Current price is: ₹2,799.00.

Book Now
Categories , ,

Aspergillus IgE, IgG, IgM Panel

The Aspergillus IgE, IgG, and IgM panel is a comprehensive test used to assess immune responses to Aspergillus fumigatus, a common fungus that can cause allergic, chronic, or invasive infections.

Why is the Aspergillus IgE, IgG, IgM Panel Done?

✅ To Diagnose Allergic Aspergillus Reactions (ABPA)

  • High IgE levels suggest Allergic Bronchopulmonary Aspergillosis (ABPA), commonly seen in asthma and cystic fibrosis patients.

✅ To Detect Chronic Aspergillus Infections (CPA, Aspergilloma)

  • High IgG levels indicate Chronic Pulmonary Aspergillosis (CPA) or aspergilloma (fungal ball).

✅ To Identify Recent or Active Infections (Invasive Aspergillosis)

  • High IgM levels may suggest an early or acute Aspergillus infection, especially in immunocompromised patients.

✅ To Monitor Aspergillus Infection Progression & Treatment Response

  • Used in patients receiving antifungal therapy to assess disease progression.

Test Procedure

🩸 Sample Type:

  • Blood sample (serum)

⏳ Turnaround Time:

  • 3–7 days

🔬 Methods Used:

  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence Assay (IFA)

Interpretation of Aspergillus IgE, IgG, and IgM Levels

Test Indicates Normal Range Positive Result Suggests
Aspergillus IgE Allergic reaction < 0.35 kU/L ABPA (Allergic Bronchopulmonary Aspergillosis)
Aspergillus IgG Chronic infection < 40 mg/L CPA (Chronic Pulmonary Aspergillosis), Aspergilloma
Aspergillus IgM Recent or acute infection < 0.35 kU/L Early-stage or invasive Aspergillosis

What Do Abnormal Aspergillus Panel Results Mean?

🔴 High Aspergillus IgE:

  • Suggests Allergic Bronchopulmonary Aspergillosis (ABPA)
  • Common in asthma, cystic fibrosis, or bronchiectasis patients.

🔴 High Aspergillus IgG:

  • Indicates Chronic Pulmonary Aspergillosis (CPA) or Aspergilloma
  • Found in patients with lung damage from TB, COPD, or fibrosis.

🔴 High Aspergillus IgM:

  • Suggests a recent or acute Aspergillus infection
  • May indicate early invasive aspergillosis in immunocompromised individuals.

🟢 Negative or Low Aspergillus IgE, IgG, and IgM:

  • Aspergillus infection or allergy is unlikely.
  • Other lung conditions (e.g., TB, bacterial pneumonia) should be considered.

Next Steps If Aspergillus Panel is Positive?

🔬 Additional Tests for Confirmation:

  • Chest CT Scan or X-ray – Detects lung cavities, nodules, or aspergilloma.
  • Sputum Culture or PCR – Confirms Aspergillus in the lungs.
  • Aspergillus Galactomannan Antigen Test – Detects invasive aspergillosis.
  • Total IgE Test – Helps confirm ABPA.

✅ Treatment Options Based on Results:

  • ABPA (High IgE): Corticosteroids + antifungals (itraconazole).
  • CPA/Aspergilloma (High IgG): Long-term antifungals (itraconazole, voriconazole).
  • Invasive Aspergillosis (High IgM): IV antifungals (voriconazole, amphotericin B).

Key Takeaways

🔹 Aspergillus IgE is a marker for allergic reactions (ABPA).
🔹 Aspergillus IgG is a marker for chronic infections (CPA, aspergilloma).
🔹 Aspergillus IgM is a marker for recent or acute infections.
🔹 Further testing (CT scan, cultures, galactomannan) is required for confirmation.
🔹 Treatment depends on the specific condition (ABPA, CPA, or invasive disease).